A new perspective on the regulation of neuroinflammation in intracerebral hemorrhage: mechanisms of NLRP3 inflammasome activation and therapeutic strategies

Intracerebral hemorrhage (ICH), a specific subtype within the spectrum of stroke disorders, is characterized by its high mortality and significant risk of long-term disability. The initiation and progression of neuroinflammation play a central and critical role in the pathophysiology of ICH. The NOD...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Kai-long He, Xian Yu, Lei Xia, Yan-dong Xie, En-bo Qi, Liang Wan, Xu-ming Hua, Chao-hui Jing
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Subjects:	intracerebral hemorrhage neuroinflammation NLRP3 inflammasome microglia astrocyte inflammation regulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526786/full