Artificial intelligence generated 3D body composition predicts dose modifications in patients undergoing neoadjuvant chemotherapy for rectal cancer

Abstract Purpose Chemotherapy administration is a balancing act between giving enough to achieve the desired tumour response while limiting adverse effects. Chemotherapy dosing is based on body surface area (BSA). Emerging evidence suggests body composition plays a crucial role in the pharmacokineti...

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Bibliographic Details

Published in:	Journal of Cancer Research and Clinical Oncology
Main Authors:	Alex Besson, Ke Cao, Ahmed Mardinli, Lara Wirth, Josephine Yeung, Rory Kokelaar, Peter Gibbs, Fiona Reid, Justin M. Yeung
Format:	Article
Language:	English
Published:	Springer 2025-05-01
Subjects:	Rectal cancer Chemotherapy Dose modification Body composition Artificial intelligence
Online Access:	https://doi.org/10.1007/s00432-025-06219-5