Dexamethasone (6 mg/m2/day) and prednisolone (60 mg/m2/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial

Dexamethasone could be more effective than prednisolone at similar anti-inflammatory doses in the treatment of childhood acute lymphoblastic leukemia. In order to check if this “superiority” of dexamethasone might be dose-dependent, we conducted a randomized phase III trial comparing dexamethasone (...

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Bibliographic Details
Published in:Haematologica
Main Authors: Carine Domenech, Stefan Suciu, Barbara De Moerloose, Françoise Mazingue, Geneviève Plat, Alina Ferster, Anne Uyttebroeck, Nicolas Sirvent, Patrick Lutz, Karima Yakouben, Martine Munzer, Pierre Röhrlich, Dominique Plantaz, Frederic Millot, Pierre Philippet, Nicole Dastugue, Sandrine Girard, Hélène Cavé, Yves Benoit, Yves Bertrandfor, Children’s Leukemia Group (CLG) of the European Organisation for Research and Treatment of Cancer (EORTC)
Format: Article
Language:English
Published: Ferrata Storti Foundation 2014-07-01
Online Access:https://haematologica.org/article/view/7087