A Parallelized Nanofluidic Device for High-Throughput Optical DNA Mapping of Bacterial Plasmids

Optical DNA mapping (ODM) has developed into an important technique for DNA analysis, where single DNA molecules are sequence-specifically labeled and stretched, for example, in nanofluidic channels. We have developed an ODM assay to analyze bacterial plasmids—circular extrachromosomal DNA that ofte...

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Bibliographic Details

Published in:	Micromachines
Main Authors:	Sriram KK, Yii-Lih Lin, Tsegaye Sewunet, Marie Wrande, Linus Sandegren, Christian G. Giske, Fredrik Westerlund
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	nanofluidics multiplexing optical DNA mapping plasmids antibiotic resistance
Online Access:	https://www.mdpi.com/2072-666X/12/10/1234