Inhibitory effect of doxycycline conjugated with deoxycholic acid and polyethylenimine conjugate on nasal fibroblast differentiation and extracellular production.

<h4>Background</h4>Chronic rhinosinusitis (CRS) is an inflammatory disease affecting the sinuses or nose. Persistent inflammatory responses can lead to tissue remodeling, which is a pathological characteristics of CRS. Activation of fibroblasts in the nasal mucosal stroma, differentiatio...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Jae-Min Shin, Hyun-Woo Yang, Su-Yeon Lim, Ji-Hoon Jeong, Il-Ho Park
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2024-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285655&type=printable