Polyglycerol-opioid conjugate produces analgesia devoid of side effects

Novel painkillers are urgently needed. The activation of opioid receptors in peripheral inflamed tissue can reduce pain without central adverse effects such as sedation, apnoea, or addiction. Here, we use an unprecedented strategy and report the synthesis and analgesic efficacy of the standard opioi...

全面介绍

书目详细资料

发表在:	eLife
Main Authors:	Sara González-Rodríguez, Mohiuddin A Quadir, Shilpi Gupta, Karolina A Walker, Xuejiao Zhang, Viola Spahn, Dominika Labuz, Antonio Rodriguez-Gaztelumendi, Martin Schmelz, Jan Joseph, Maria K Parr, Halina Machelska, Rainer Haag, Christoph Stein
格式:	文件
语言:	英语
出版:	eLife Sciences Publications Ltd 2017-07-01
主题:	pain inflammation opioid nanocarrier polymer
在线阅读:	https://elifesciences.org/articles/27081