Silica Particles Mediate Phenotypic and Functional Alteration of Dendritic Cells and Induce Th2 Cell Polarization

During silicosis, immune cells, including macrophages, T cells, B cells, and NK cells, participate in fibrosis development through alteration of the immune status. Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with a key role in initiating immune responses and sustaining imm...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Suna Liu, Changfu Hao, Lei Bao, Dehua Zhao, Hongyi Zhang, Jianyong Hou, Di Wang, Huiting Chen, Feifei Feng, Wu Yao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-04-01
Subjects:	dendritic cells silica silicosis alveolar macrophages phagocytosis Th2 polarization
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00787/full