The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence

Abstract Background Genetic mitochondrial diseases represent a significant challenge to human health. These diseases are extraordinarily heterogeneous in clinical presentation and genetic origin, and often involve multi-system disease with severe progressive symptoms. Mitochondrial diseases represen...

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Bibliographic Details
Published in:Orphanet Journal of Rare Diseases
Main Authors: Allison Hanaford, Simon C. Johnson
Format: Article
Language:English
Published: BMC 2022-09-01
Subjects:
Mitochondrial disease
Leigh syndrome
MELAS
Immunity
Genetic disease
Online Access:https://doi.org/10.1186/s13023-022-02495-3

Internet

https://doi.org/10.1186/s13023-022-02495-3

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