Host-pathogen relationship in retreated tuberculosis with major rifampicin resistance–conferring mutations

IntroductionIt is assumed that host defense systems eliminating the pathogen and regulating tissue damage make a strong impact on the outcome of tuberculosis (TB) disease and that these processes are affected by rifampicin (RIF) resistance–conferring mutations of Mycobacterium tuberculosis (Mtb). Ho...

Full description

Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Nguyen Thi Le Hang, Minako Hijikata, Shinji Maeda, Pham Huu Thuong, Hoang Van Huan, Nguyen Phuong Hoang, Do Bang Tam, Pham Thu Anh, Nguyen Thu Huyen, Vu Cao Cuong, Nobuyuki Kobayashi, Keiko Wakabayashi, Akiko Miyabayashi, Shintaro Seto, Naoto Keicho
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Subjects:	Mycobacterium tuberculosis recurrence rifampicin resistance rpoB variants whole genome sequencing blood transcriptomic signatures
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1187390/full