Genomic subtypes of non-muscle-invasive bladder cancer: guiding immunotherapy decision-making for patients exposed to aristolochic acid

Abstract Background The limited genomic data on non-muscle-invasive bladder cancer (NMIBC) hampers our understanding of its carcinogenesis and development. Specifically, Aristolochic acid (AA), a potent human carcinogenic compound from aristolochia plants and commonly found in Chinese herbal medicin...

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Bibliographic Details
Published in:Molecular Medicine
Main Authors: Yun Peng, Yuxuan Song, Caipeng Qin, Mengting Ding, Zixiong Huang, Fei Wang, Yuchao HuangFu, Luping Yu, Yiqing Du, Tao Xu
Format: Article
Language:English
Published: BMC 2025-04-01
Subjects:
Non-muscle-invasive bladder cancer
Aristolochic acid
Genomic subtypes
Immunotherapy
Bacillus Calmette-Guerin
Online Access:https://doi.org/10.1186/s10020-025-01199-1

Internet

https://doi.org/10.1186/s10020-025-01199-1

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