Inactivation of KDM6A promotes the progression of colorectal cancer by enhancing the glycolysis

Abstract KDM6A (lysine demethylase 6A) has been reported to undergo inactivating mutations in colorectal cancer, but its function in the progression of colorectal cancer has not been evaluated using animal models of colorectal cancer. In this study, we found that knocking out KDM6A expression in mou...

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出版年:	European Journal of Medical Research
主要な著者:	Dexiang Zhang, Xiaohong Zhao, Yu Gao, Meixing Wang, Mi Xiao, Kaihua Zhu, Wei Niu, Yuedi Dai
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-06-01
主題:	KDM6A Colorectal cancer LDHA Cancer metabolism
オンライン･アクセス:	https://doi.org/10.1186/s40001-024-01828-1