Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche

Mesenchymal stem cells (MSCs) within their native environment of the stem cell niche in bone receive biochemical stimuli from surrounding cells. These stimuli likely influence how MSCs differentiate to become bone precursors. The ability of MSCs to undergo osteogenic differentiation is well establis...

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Bibliographic Details

Published in:	European Cells & Materials
Main Authors:	LM McNamara, G Shaw, FP Barry, GL Niebur, PE McHugh, E Birmingham
Format:	Article
Language:	English
Published:	Forum Multimedia Publishing LLC 2012-01-01
Subjects:	Bone mesenchymal stem cells osteogenesis osteoblast osteocyte in vitro niche
Online Access:	http://www.ecmjournal.org/journal/papers/vol023/pdf/v023a02.pdf