Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach

The rise in type 1 diabetes is thought to be related to increased childhood obesity, but this relationship is not well understood. In this study, the authors utilize Mendelian randomization to separate the direct and indirect effects of childhood body size on risk of type 1 diabetes and 7 other immu...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Tom G. Richardson, Daniel J. M. Crouch, Grace M. Power, Fernanda Morales-Berstein, Emma Hazelwood, Si Fang, Yoonsu Cho, Jamie R. J. Inshaw, Catherine C. Robertson, Carlo Sidore, Francesco Cucca, Steven S. Rich, John A. Todd, George Davey Smith
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Online Access:https://doi.org/10.1038/s41467-022-29932-y