LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1

Abstract Considering the effect of SIRT1 on improving myocardial fibrosis and GAS5 inhibiting occurrence and development of myocardial fibrosis at the cellular level, the aim of the present study was to investigate whether LncRNA GAS5 could attenuate cardiac fibrosis through regulating mir-217/SIRT1...

Full description

Bibliographic Details
Published in:Scientific Reports
Main Authors: Yan-hong Zhang, Ting-ting Sun, Zhen-hua Liu, Xu Li, Xiao-Fang Fan, Li-ping Han
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Subjects:
GAS5
SIRT1
Mir-217
Myocardial fibrosis
Pyroptosis
Online Access:https://doi.org/10.1038/s41598-024-58239-9

Internet

https://doi.org/10.1038/s41598-024-58239-9

Similar Items