Virus evolution and reduced viral viability during treatment of persistent COVID-19 Omicron BA.5 infection in an immunocompromised host

We present the clinical course of a 72-year-old female with COVID-19 and a history of hematologic stem cell transplantation for acute myeloid leukemia. We performed serial analyses of viral load and whole-genome amplification. The virus growth was evaluated by a real-time polymerase chain reaction a...

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Bibliographic Details

Published in:	International Journal of Infectious Diseases
Main Authors:	Hiroyasu Kaya, Hideki Tani, Noriko Inasaki, Shunsuke Yazawa, Masae Itamochi, Daiki Higashi, Noriaki Tsuji, Masahiko Nakamura, Kazunori Oishi
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Subjects:	SARS-CoV-2 Persistent infection Immunocompromised patients Amino acid mutation
Online Access:	http://www.sciencedirect.com/science/article/pii/S120197122300721X