An Improved Synthesis of Some 5-Substituted Indolizines Using Regiospecific Lithiation

Various 2-substituted indolizines can be directly and selectively lithiated in the 5 position and subsequent reactions with different electrophiles lead to some novel classes of indolizines. In particular, previously unknown 5-formyl- and 5-iodoindolizine have been prepared by this way and the molec...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Eugene V. Babaev, Viktor B. Rybakov, Alexander A. Bush, Alexey G. Kuznetsov
Format:	Article
Language:	English
Published:	MDPI AG 2005-09-01
Subjects:	Direct lithiation 5-lithiumindolizine 5-formylindolizine 5-iodoindolizine 5-benzoylindolizine Suzuki reaction reduction oxime.
Online Access:	http://www.mdpi.com/1420-3049/10/9/1074/