Transcriptomic characterization of the human segmental endotoxin challenge model

Abstract Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy safely induces transient airway inflammation in human lungs. This model enables investigation of pulmonary inflammatory mechanisms as well as pharmacodynamic analysis of investigational drugs. The aim of this work was to des...

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发表在:Scientific Reports
Main Authors: Christina Gress, Tobias Litzenburger, Ramona Schmid, Ke Xiao, Florian Heissig, Meike Muller, Abhya Gupta, Jens M. Hohlfeld
格式: 文件
语言:英语
出版: Nature Portfolio 2024-01-01
在线阅读:https://doi.org/10.1038/s41598-024-51547-0