Adipocytes Promote Cisplatin Resistance through Secreting A1BG and Regulating NAMPT/PARP1 Axis‐Mediated DNA Repair in Osteosarcoma

Abstract Obesity is increasingly recognized as a negative prognostic factor for cancers, including osteosarcoma. However, the mechanisms linking obesity to chemoresistance in osteosarcoma remain unclear. This study found obesity is significantly associated with poor responses to cisplatin‐based chem...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Yonghui Liang, Zhaohui Li, Lina Tang, Zhen Pan, Xiang Fei, Chen Tan, Aina He, Qingcheng Yang, Dongdong Cheng
Format:	Article
Language:	English
Published:	Wiley 2025-09-01
Subjects:	adipocytes cisplatin resistance dna repair osteosarcoma
Online Access:	https://doi.org/10.1002/advs.202502926