Recombinant PASylated nanobody probes with improved blood circulation and tumor targeting

Nanobodies have been extensively demonstrated in biomedical imaging and therapy. However, nanobody probes often suffer from rapid renal clearance due to its small size. Herein, we reported a recombinant nanobody with a 200 amino-acid polypeptide chain consisting of Pro, Ala, and Ser (PAS) at the C-t...

Full description

Bibliographic Details

Published in:	Journal of Innovative Optical Health Sciences
Main Authors:	Yicheng Yang, Lingyue Jin, You Zhang, Siyu Zhou, Weijun Wei, Gang Huang, Changfeng Wu
Format:	Article
Language:	English
Published:	World Scientific Publishing 2025-05-01
Subjects:	Nanobody PASylation fluorescence tumor targeting
Online Access:	https://www.worldscientific.com/doi/10.1142/S1793545825410019