Efflux-Mediated Resistance in <i>Enterobacteriaceae</i>: Recent Advances and Ongoing Challenges to Inhibit Bacterial Efflux Pumps

Efflux is one of the key mechanisms used by Gram-negative bacteria to reduce internal antibiotic concentrations. These active transport systems recognize and expel a wide range of toxic molecules, including antibiotics, thereby contributing to reduced antibiotic susceptibility and allowing the bacte...

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Bibliographic Details

Published in:	Antibiotics
Main Authors:	Florent Rouvier, Jean-Michel Brunel, Jean-Marie Pagès, Julia Vergalli
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	accumulation assay adjuvants and inhibitors antibiotics efflux pumps fluorometry Gram-negative bacteria
Online Access:	https://www.mdpi.com/2079-6382/14/8/778