Influence of Formulation Parameters on Redispersibility of Naproxen Nanoparticles from Granules Produced in a Fluidized Bed Process

The particle size reduction of active pharmaceutical ingredients is an efficient method to overcome challenges associated with a poor aqueous solubility. With respect to stability and patient’s convenience, the corresponding nanosuspensions are often further processed to solid dosage forms. In this...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Martin Wewers, Stefan Czyz, Jan Henrik Finke, Edgar John, Bernard Van Eerdenbrugh, Michael Juhnke, Heike Bunjes, Arno Kwade
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Subjects:	wet media milling poor aqueous solubility naproxen API nanosuspension fluidized bed granulation formulation parameters
Online Access:	https://www.mdpi.com/1999-4923/12/4/363