Killer instincts: natural killer cells as multifactorial cancer immunotherapy

Natural killer (NK) cells integrate heterogeneous signals for activation and inhibition using germline-encoded receptors. These receptors are stochastically co-expressed, and their concurrent engagement and signaling can adjust the sensitivity of individual cells to putative targets. Against cancers...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Sarah Nersesian, Emily B. Carter, Stacey N. Lee, Lauren P. Westhaver, Jeanette E. Boudreau
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Subjects:	natural killer cells killer immunoglobulin-like receptors (KIR) signal integration cancer immunotherapy innate lymphoid cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1269614/full