TRIO RVEMVS: A Bayesian framework for rare variant association analysis with expectation-maximization variable selection using family trio data.

It is commonly reported that rare variants may be more functionally related to complex diseases than common variants. However, individual rare variant association tests remain challenging due to low minor allele frequency in the available samples. This paper proposes an expectation maximization vari...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Duo Yu, Matthew Koslovsky, Margaret C Steiner, Kusha Mohammadi, Chenguang Zhang, Michael D Swartz
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2024-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0314502