Oxidative and carbonyl stress induced AMD and Codonopsis lanceolata ameliorates AMD via controlling oxidative and carbonyl stress

Abstract Age-related macular degeneration (AMD) is one of the leading causes of blindness. AMD is currently incurable; the best solution is to prevent its occurrence. To develop drugs for AMD, it is crucial to have a model system that mimics the symptoms and mechanisms in patients. It is most import...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Soon-Young Lee, Yeon-Kyoung Cho, Chun-Sik Bae, Gyeyeop Kim, Min-Jae Lee, Seung-Sik Cho, In-Chul Jeon, Dae-Hun Park
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-07-01
Subjects:	Age-related macular degeneration (AMD) Codonopsis lanceolata Oxidative/carbonyl stress Keap1/Nrf2/HO-1 pathway 4-HNE Apoptosis
Online Access:	https://doi.org/10.1038/s41598-024-67044-3