Chronic Excitotoxin-Induced Axon Degeneration in a Compartmented Neuronal Culture Model

Glutamate excitotoxicity is a major pathogenic process implicated in many neurodegenerative conditions, including AD (Alzheimer's disease) and following traumatic brain injury. Occurring predominantly from over-stimulation of ionotropic glutamate receptors located along dendrites, excitotoxic a...

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Bibliographic Details
Published in:ASN Neuro
Main Authors: Katherine A Hosie, Anna E King, Catherine A Blizzard, James C Vickers, Tracey C Dickson
Format: Article
Language:English
Published: Taylor & Francis 2012-02-01
Online Access:https://doi.org/10.1042/AN20110031