Comparison of the efficacy and safety of low-dose calcineurin inhibitors plus sirolimus plus mycophenolic acid with the standard-dose calcineurin inhibitors plus mycophenolic acid regimen in patients who received kidney transplants

BackgroundSirolimus (SRL) has shown its anti-rejection and renoprotective efficacy in patients with kidney transplantation. However, more evidence is still needed. The current study aimed to evaluate the efficacy and safety of an SRL-containing regimen in patients who received kidney transplants.Met...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Li Li, Jiao Wan, Yizhi Li, Jiali Fang, Guanghui Li, Junjie Ma, Zheng Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	calcineurin inhibitors sirolimus kidney transplant renoprotective safety
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1631055/full