The Fis Nucleoid Protein Negatively Regulates the Phase Variation fimS Switch of the Type 1 Pilus Operon in Enteropathogenic Escherichia coli

In Escherichia coli the expression of type 1 pili (T1P) is determined by the site-specific inversion of the fimS ON–OFF switch located immediately upstream of major fimbrial subunit gene fimA. Here we investigated the role of virulence (Ler, GrlR, and GrlA) and global regulators (H-NS, IHF, and Fis)...

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发表在:Frontiers in Microbiology
Main Authors: Zeus Saldaña-Ahuactzi, Jorge Soria-Bustos, Verónica I. Martínez-Santos, Jorge A. Yañez-Santos, Ygnacio Martínez-Laguna, María Lilia Cedillo-Ramirez, José L. Puente, Jorge A. Girón
格式: 文件
语言:英语
出版: Frontiers Media S.A. 2022-04-01
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在线阅读:https://www.frontiersin.org/articles/10.3389/fmicb.2022.882563/full