Cross-Neutralization of Distant Coronaviruses Strongly Correlates with Spike S2-Specific Antibodies from Immunocompetent and Immunocompromised Vaccinated SARS-CoV-2-Infected Patients

<b>Background/Objectives</b>: Despite the lifting of the COVID-19 public health emergency, SARS-CoV-2 infections continue to be recorded worldwide. The continued prevalence of infection has been attributed to the ability of the virus to evade host immune responses, including neutralizing...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Sara V. Patel, Brooke M. Leeman, Patricia J. Botros, Joanna Folta, Dhiman Shahid, Anya I. Rocque, Andrew S. Joyal, Joseph A. Vecchio, Eliza Passell, Dessie Tien, Zahra Reynolds, Karry Su, Tammy D. Vyas, Jatin M. Vyas, Emory Abar, Mamadou Barry, Andrew Alexandrescu, Zachary Wallace, Jeffrey M. DaCosta, Manish C. Choudhary, Trevor J. Tamura, Gregory E. Edelstein, Yijia Li, Rinki Deo, Jeffrey A. Sparks, Julie Boucau, Owen T. Glover, Amy K. Barczak, Jacob Lemieux, Mark J. Siedner, Jonathan Z. Li, Ismael Ben Fofana
Format:	Article
Language:	English
Published:	MDPI AG 2025-09-01
Subjects:	SARS-CoV-2 COVID-19 neutralizing antibodies S2-specific antibodies spike-S1 dominance immunocompromised
Online Access:	https://www.mdpi.com/2076-393X/13/9/949