Adenosine A1 Receptor-Mediated Synaptic Depression in the Developing Hippocampal Area CA2

Immunolabeling for adenosine A1 receptors (A1Rs) is high in hippocampal area CA2 in adult rats, and the potentiating effects of caffeine or other A1R-selective antagonists on synaptic responses are particularly robust at Schaffer collateral synapses in CA2. Interestingly, the pronounced staining for...

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Bibliographic Details

Published in:	Frontiers in Synaptic Neuroscience
Main Authors:	Douglas A. Caruana, Serena M. Dudek
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-06-01
Subjects:	adenosine phosphodiesterase adenylyl cyclase synapse long-term depression (LTD) hippocampus
Online Access:	https://www.frontiersin.org/article/10.3389/fnsyn.2020.00021/full