A Mouse Model for the Rapid and Binomial Assessment of Putative WNT/β-Catenin Signalling Inhibitors

Specific signalling thresholds of the WNT/β-catenin pathway affect embryogenesis and tissue homeostasis in the adult, with mutations in this pathway frequently occurring in cancer. Excessive WNT/β-catenin activity inhibits murine anterior development associated with embryonic lethality and accounts...

詳細記述

書誌詳細

出版年:	Biomedicines
主要な著者:	Janson Tse, Ryan O’Keefe, Angela Rigopolous, Annalisa L. E. Carli, Jo Waaler, Stefan Krauss, Matthias Ernst, Michael Buchert
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2023-10-01
主題:	WNT/β-catenin signalling WNT inhibitors in vivo assay tankyrase inhibitor pyrvinium pamoate <i>APC</i>
オンライン･アクセス:	https://www.mdpi.com/2227-9059/11/10/2719