Rationale and design of STAMINA: Senolytics to alleviate mobility issues and neurological impairments in aging, a geroscience feasibility study

The process of cellular senescence is hypothesized to play a critical role in the development of age-related mobility and cognitive impairments, both of which precede the development of Alzheimer's disease. Therefore, senolytic compounds that eliminate senescent cells represent an alternative s...

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Bibliographic Details
Published in:Translational Medicine of Aging
Main Authors: Courtney L. Millar, Ike Iloputaife, Kathryn Baldyga, Jasmin Kuo, Tamara Tchkonia, James L. Kirkland, Thomas G. Travison, Lewis A. Lipsitz
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-01-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468501123000159