A collagen-based bilayer nanocomposite scaffold for osteochondral tissue regeneration: integrating hydroxyapatite and cellulose nanocrystals

Abstract Regenerating osteochondral (OC) defects remains a significant challenge in regenerative medicine due to the complex nature of these tissues and their limited self-healing capacity. While tissue engineering offers a promising solution, developing a comprehensive, long-term regenerative strat...

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Bibliographic Details

Published in:	Journal of Materials Science: Materials in Medicine
Main Authors:	Fatemeh Mahmoudi, Sara Takallu, Mohammad Ali Derakhshan, Esmaeil Mirzaei
Format:	Article
Language:	English
Published:	Springer 2025-10-01
Subjects:	Osteochondral defects Collagen hydrogel Hydroxyapatite Cellulose nanocrystals Layered scaffold
Online Access:	https://doi.org/10.1007/s10856-025-06953-9