Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors?

It is generally assumed that selective serotonin reuptake inhibitors (SSRIs) induce antidepressant activity by inhibiting serotonin (5-HT) reuptake transporters, thus elevating synaptic 5-HT levels and, finally, ameliorates depression symptoms. New evidence indicates that SSRIs may also modulate oth...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Molecules
المؤلفون الرئيسيون:	Hugo R. Arias, Katarzyna M. Targowska-Duda, Jesús García-Colunga, Marcelo O. Ortells
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2021-04-01
الموضوعات:	selective serotonin reuptake inhibitors antidepressants nicotinic acetylcholine receptors noncompetitive antagonists neuronal pathways molecular modeling
الوصول للمادة أونلاين:	https://www.mdpi.com/1420-3049/26/8/2149