Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

Background Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts its distinct pharmacological effects compared to...

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Bibliographic Details

Published in:	Molecular Pain
Main Authors:	Seira Doi BS, Tomohisa Mori PhD, Naoki Uzawa MS, Takamichi Arima BA, Tomoyuki Takahashi BA, Masashi Uchida BS, Ayaka Yawata BA, Michiko Narita BS, Yasuhito Uezono PhD, Tsutomu Suzuki PhD, Minoru Narita PhD
Format:	Article
Language:	English
Published:	SAGE Publishing 2016-06-01
Online Access:	https://doi.org/10.1177/1744806916654146