Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape

Abstract Maspin/SerpinB5 is an abundant and pleiotropic protein mostly expressed by epithelia. Initially described as a tumor suppressor, it has been reported as a regulator of cell adhesion, migration, and invasion. How intracellular Maspin orchestrates these processes is poorly understood. In this...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Luiz E. da Silva, Lia M. G. Paim, Tatiana Lyalina, Ana P. J. Menezes, Julia P. C. da Cunha, Susanne Bechstedt, Nathalie Cella
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Online Access:	https://doi.org/10.1038/s42003-025-08688-3