HER2 status of CTCs by peptide-functionalized nanoparticles as the diagnostic biomarker of breast cancer and predicting the efficacy of anti-HER2 treatment

Efficacy of anti-human epidermal growth factor receptor 2 (HER2) treatment is impacted by tissue-based evaluation bias due to tumor heterogeneity and dynamic changes of HER2 in breast cancer. Circulating tumor cell (CTC)-based HER2 phenotyping provides integral and real-time assessment, benefiting a...

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Bibliographic Details

Published in:	Frontiers in Bioengineering and Biotechnology
Main Authors:	Mengting Wang, Yaxin Liu, Bin Shao, Xiaoran Liu, Zhiyuan Hu, Chen Wang, Huiping Li, Ling Zhu, Ping Li, Yanlian Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Subjects:	circulating tumor cells peptide nanomaterials HER2 phenotyping prognosis breast cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.1015295/full