Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats

Estrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors mod...

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Bibliographic Details

Published in:	Current Issues in Molecular Biology
Main Authors:	Anna Pilutin, Sylwia Rzeszotek, Aleksandra Wilk, Klaudia Klimaszewska, Julia Łukasiewicz, Rufaro Lynnette Mafuta, Thanushan Nagendran, Rupia Ndambara, Barbara Wiszniewska
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Subjects:	estrogens male small intestine aromatase letrozole morphology
Online Access:	https://www.mdpi.com/1467-3045/46/3/127