The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia

Abstract Background Over-activated microglia play a central role during neuroinflammation, leading to neuronal cell death and neurodegeneration. Reversion of over-activated to neuroprotective microglia phenotype could regenerate a healthy CNS-supporting microglia environment. Our aim was to identify...

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Bibliographic Details
Published in:Journal of Neuroinflammation
Main Authors: Veronika E. Neubrand, Irene Forte-Lago, Marta Caro, Mario Delgado
Format: Article
Language:English
Published: BMC 2018-12-01
Subjects:
Microglia
Neuroinflammation
siRNA screen
Cell morphology
Online Access:http://link.springer.com/article/10.1186/s12974-018-1386-z

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http://link.springer.com/article/10.1186/s12974-018-1386-z

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