STAG2 regulates polycomb and differentiation in urothelial precursors and bladder cancer.

The STAG2 tumor suppressor gene is commonly inactivated by mutations in a wide range of common cancer types. STAG2 encodes a component of the cohesin complex, which controls sister chromatid cohesion and 3D genome organization. In bladder cancer, STAG2 mutations are most common in the earliest low-g...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Youngrok Park, Wanying Xu, Tianyi Yang, Victoria Hill, Xiaoyuan He, Lisa Sadzewicz, Luke Tallon, Jung-Sik Kim, Fulai Jin, Todd Waldman
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0333128