TCRpred: incorporating T-cell receptor repertoire for clinical outcome prediction

T-cell receptor (TCR) plays critical roles in recognizing antigen peptides and mediating adaptive immune response against disease. High-throughput technologies have enabled the sequencing of TCR repertoire at the single nucleotide level, allowing researchers to characterize TCR sequences with high r...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Meiling Liu, Yang Liu, Li Hsu, Qianchuan He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Subjects:	CDR3 clinical outcome prediction high dimensions high throughput sequencing T-cell receptor TCR repertoire
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2024.1345559/full