Oxidative insults disrupt OPA1-mediated mitochondrial dynamics in cultured mammalian cells

Objective: To explore the impact of oxidative insults on mitochondrial dynamics. In mammalian cells, oxidative insults activate stress response pathways including inflammation, cytokine secretion, and apoptosis. Intriguingly, mitochondria are emerging as a sensitive network that may function as an e...

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Bibliographic Details

Published in:	Redox Report
Main Authors:	Iraselia Garcia, Wendy Innis-Whitehouse, Alma Lopez, Megan Keniry, Robert Gilkerson
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2018-01-01
Subjects:	Transmembrane potential oxidative stress H2O2 OPA1 OMA1 fusion
Online Access:	http://dx.doi.org/10.1080/13510002.2018.1492766