The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles

N6-methyladenosine (m6A), the most abundant mRNA modification, is deposited in mammals/insects/plants by m6A methyltransferase complexes (MTC) comprising a catalytic subunit and at least five additional proteins. The yeast MTC is critical for meiosis and was known to comprise three proteins, of whic...

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Bibliographic Details

Published in:	eLife
Main Authors:	Imke Ensinck, Alexander Maman, Waleed S Albihlal, Michelangelo Lassandro, Giulia Salzano, Theodora Sideri, Steven A Howell, Enrica Calvani, Harshil Patel, Guy Bushkin, Markus Ralser, Ambrosius P Snijders, Mark Skehel, Ana Casañal, Schraga Schwartz, Folkert J van Werven
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2023-07-01
Subjects:	N6-methyladenosine methyltransferase complex m6A MTC Ime4 Vir1
Online Access:	https://elifesciences.org/articles/87860