Providing biomimetic microenvironment for pulp regeneration via hydrogel-mediated sustained delivery of tissue-specific developmental signals

Regenerative endodontic therapy is a promising approach to restore the vitality of necrotic teeth, however, pulp regeneration in mature permanent teeth remains a substantial challenge due to insufficient developmental signals. The dentin is embryologically and histologically similar to the pulp, whi...

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Bibliographic Details

Published in:	Materials Today Bio
Main Authors:	Zhuo Xie, Peimeng Zhan, Xinfang Zhang, Shuheng Huang, Xuetao Shi, Zhengmei Lin, Xianling Gao
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	Dentin matrix Biomimetic hydrogels Pulp regeneration Dental pulp stem cells Tissue engineering
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590006424001613