XBP-1 Remodels Lipid Metabolism to Extend Longevity

Summary: The endoplasmic reticulum unfolded protein response (UPRER) is a cellular stress response that maintains homeostasis within the secretory pathway, regulates glucose and lipid metabolism, and influences longevity. To ask whether this role in lifespan determination depends upon metabolic inte...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Soudabeh Imanikia, Ming Sheng, Cecilia Castro, Julian L. Griffin, Rebecca C. Taylor
Format:	Article
Language:	English
Published:	Elsevier 2019-07-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124719308307