Theoretical design for covering Engeletin with functionalized nanostructure-lipid carriers as neuroprotective agents against Huntington’s disease via the nasal-brain route

Objective: To propose a theoretical formulation of engeletin-nanostructured lipid nanocarriers for improved delivery and increased bioavailability in treating Huntington’s disease (HD).Methods: We conducted a literature review of the pathophysiology of HD and the limitations of currently available m...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Smriti, Madhav Singla, Saurabh Gupta, Omji Porwal, Dalal Nasser Binjawhar, Amany A. Sayed, Pooja Mittal, Fatma M. El-Demerdash, Mohammad Algahtani, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta, Puneet Bawa, Ahmed E. Altyar, Mohamed M. Abdel-Daim
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Subjects:	Huntington disease engeletin phytoconstituent neuroprotective intranasal nano formulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1218625/full