Functional study of residual iCre activity relevant for split-Cre applications

Cre-lox system is a major tool in mouse molecular genetics instrumental in promoting somatic recombination to spatiotemporally control transcriptional activation/inhibition in subsets of cells or tissues in vivo. A critical factor behind this system may be represented by the availability of a specif...

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Bibliographic Details

Published in:	Current Research in Biotechnology
Main Authors:	Antea Minetti, Noemi Barsotti, Massimo Pasqualetti
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Subjects:	iCre recombinase Cre/loxP system Split-Cre Somatic recombination Animal Models
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590262824000893