The rise of rat models for Duchenne muscular dystrophy and therapeutic evaluations

Abstract Duchenne muscular dystrophy (DMD) is a devastating X-linked neuromuscular disorder characterized by the absence of a functional dystrophin, leading to progressive muscle loss responsible for cardiorespiratory failure and premature death. While mouse, dog, and pig models have long supported...

詳細記述

書誌詳細

出版年:	Skeletal Muscle
主要な著者:	Frederic Relaix, Peggy Lafuste, Valentina Taglietti, Laurent Tiret
フォーマット:	論文
言語:	英語
出版事項:	BMC 2025-09-01
主題:	DMD mutations Becker Muscular Dystrophy Rodent models Dystrophin isoforms Preclinical modeling Myonecrosis
オンライン･アクセス:	https://doi.org/10.1186/s13395-025-00395-1