DLK1 and DLK2, two non-canonical ligands of NOTCH receptors, differentially modulate the osteogenic differentiation of mesenchymal C3H10T1/2 cells

Abstract Background C3H10T1/2 is a mesenchymal cell line capable of differentiating into osteoblasts, adipocytes and chondrocytes. The differentiation of these cells into osteoblasts is modulated by various transcription factors, such as RUNX2. Additionally, several interconnected signaling pathways...

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Bibliographic Details

Published in:	Biological Research
Main Authors:	María-Milagros Rodríguez-Cano, María-Julia González-Gómez, Eva-María Monsalve, María-José M. Díaz-Guerra, Moustapha Kassem, Jorge Laborda, María-Luisa Nueda, Victoriano Baladrón
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Subjects:	DLK NOTCH Mesenchymal C3H10T1/2 cells Osteogenesis ERK1/2 MAPK p38 MAPK
Online Access:	https://doi.org/10.1186/s40659-024-00561-7