Hypobaric hypoxia aggravates neuroinflammation in ligature-induced periodontitis mice via the STAT3 signaling pathway

Background and purposeStudies have shown that inflammation is a key risk factor for altitude sickness in hypobaric hypoxia environments. Periodontitis, a common oral disease, is prevalent among many individuals. This study aimed to investigate the onset and progression of neuroinflammation in mice w...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Lu Chen, Jiayi Zhang, Xuechao Fei, Jiajing Wang, Jiayue Gao, Xiangpei Yue, Yaqun Jiang, Zibi Shi, Shaojie Zhang, Xiufang Jiang, Wenyue Chang, Zhonghua Dai, Jianjun Guo, Tong Zhao, Xiaoxia Jiang, Lingling Zhu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	hypobaric hypoxia periodontitis neuroinflammation STAT3
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600035/full