CD103+CD8+ tissue‐resident memory T lymphocytes of melanoma boost anti‐tumour immunity and predict immunotherapy outcomes

Abstract Background Immunotherapy has revolutionised melanoma treatment, providing significant clinical benefits by reactivating the anti‐tumour immune system. CD8+ tissue‐resident memory T lymphocytes (CD8+ TRM) have emerged as crucial mediators of anti‐tumour immunity, while their specific role in...

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Bibliographic Details

Published in:	Clinical and Translational Medicine
Main Authors:	Tianyi Zhang, Junquan Song, Yinlam Li, Kangjie Shen, Jiangying Xuan, Yuan Gao, Lili Lu, Zhi Pang, Lu Wang, Yang Yang, Zixu Gao, Qianrong Hu, Yu Zhu, Chenlu Wei, Shaoluan Zheng, Rongkui Luo, Yingyong Hou, Yuhong Zhou, Chuanyuan Wei, Jianying Gu
Format:	Article
Language:	English
Published:	Wiley 2025-09-01
Subjects:	immunotherapy melanoma TIL tissue‐resident memory T lymphocytes
Online Access:	https://doi.org/10.1002/ctm2.70464